NEW LISTERINE® CLINICAL SOLUTIONS

SUPERPOWERED SOLUTIONS

Our most scientifically advanced mouthrinses, LISTERINE® CLINICAL SOLUTIONS mouthwashes help patients address gum, teeth, and bad-breath issues between visits.

FROM THE EXPERTS IN THE SCIENCE OF MOUTHWASH

LISTERINE® CLINICAL SOLUTIONS represent the pinnacle of our long-standing history of science-based mouthrinses—a heritage that is unequalled in innovation and clinical research.
And because we are experts in mouthrinse, our products are designed to be safe and effective for your patients. We are proud to say new LISTERINE® CLINICAL SOLUTIONS mouthwashes take this to a new level.

OUR MOST ADVANCED MOUTHWASH FORMULATION FOR GUM HEALTH

Clinically proven to reduce bleeding gums by 64% in 1 week with its unique new formula with more zinc1,2*

Listerine Clinical Solutions Gum Health 67% more zinc

64% less bleeding in 1 week1*

  • This unique mouthwash formula with 67% more zinc than any other LISTERINE zinc product.2 Works in 2 ways to restore gingival health3-5

  • This formula with more zinc shifts the microbiome to a healthier state by reducing subgingival bacteria3

  • The essential oils kill 99.9% of the germs that cause plaque and gingivitis throughout the mouth4,5

64% less bleeding in 1 week1*

Listerine Clinical Solutions Gum Health top half of bottle
  • This unique mouthwash formula with 67% more zinc than any other LISTERINE zinc product. 2 Works in 2 ways to restore gingival health 3-5

  • This formula with more zinc shifts the microbiome to a healthier state by reducing subgingival bacteria 3

  • The essential oils kill 99.9% of the germs that cause plaque and gingivitis throughout the mouth 4,5

MEAN EXPANDED BLEEDING INDEX

Unique formula with 67% more zinc than any other LISTERINE zinc product2. Works in 2 ways to restore gingival health.3-5

Listerine Clinical Solutions Gum Health mean expanded bleeding index
Listerine Clinical Solutions Gum Health top half of bottle

GUM HEALTH PRODUCT PAGE

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OUR MOST ADVANCED MOUTHWASH FORMULATION FOR STRENGTHENING TEETH

Provides 3x stronger teeth and helps facilitate the release of additional calcium and phosphate ions from saliva2

Listerine Clinical Solutions Breath Defense 7 times greater fluoride

3X STRONGER TEETH2†

  • 7x greater fluoride uptake and 68% greater remineralization than ACT® Total Care Anticavity Fluoride Mouthwash2

  • Fluoride infuses into the tooth, replacing weak enamel with stronger fluorapatite that strengthens the enamel matrix

    • Provides 24-hour cavity protection (when used twice daily)

3X STRONGER TEETH 2†

Listerine Clinical Solutions Teeth Strength top half of bottle
  • 7x greater fluoride uptake and 68% greater remineralization than ACT® Total Care Anticavity Fluoride Mouthwash2

  • Fluoride infuses into the tooth, replacing weak enamel with stronger fluorapatite that strengthens the enamel matrix

       • Provides 24-hour cavity protection (when used twice daily)

RAPID FUSION TECHNOLOGY®

rapidly binds calcium ions with fluoride to create fluoride reservoirs

SEE PRODUCT INFORMATION
Rapid fusion technology

POWERED BY
RAPID FUSION
TECHNOLOGY®
a powerful fluoride-
delivery system2

Listerine Clinical Solutions Teeth Strength top half of bottle

STRENGTHENING TEETH PRODUCT PAGE

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OUR MOST ADVANCED MOUTHWASH FORMULATION FOR STUBBORN BAD BREATH

24-hour bad-breath protection with LISTERINE’s most effective odor-neutralizing mouthwash technology

Listerine Clinical Solutions Breath Defense neutralizes malodor

FIGHTS BAD BREATH FOR 24 HOURS2‡

  • Neutralizes stubborn bad breath for 24 hours2‡

  • Is clinically proven to prevent—and significantly reduce—morning breath2,6

  • Neutralizes and kills 2 sources of malodor2,6

    • Zinc and ODOR NEUTRALIZING TECHNOLOGY neutralize food and odor molecules (ie, coffee, garlic, onion)

FIGHTS BAD BREATH FOR 24 HOURS2‡

Listerine Clinical Solutions Breath Defense top half of bottle
  • Neutralizes stubborn bad breath for 24 hours2‡

  • Is clinically proven to prevent—and significantly reduce—morning breath2,6

  • Neutralizes and kills 2 sources of malodor2,6
       • Zinc and ODOR NEUTRALIZING TECHNOLOGY neutralize food and odor molecules (ie, coffee, garlic, onion)

ORGANOLEPTIC MEASURES

Neutralizes stubborn bad breath for 24 hours2‡

Listerine Clinical Solutions Breath Defense Oral Malodor Intensity

LISTERINE’s unique
odor-neutralizing
technology

TRIPLE-ACTION FORMULA
immediately kills odor-causing bacteria to fight bad breath5,7

Listerine Clinical Solutions triple-action formula
Listerine Clinical Solutions Breath Defense top half of bottle

BREATH DEFENSE PRODUCT PAGE

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SAFETY INFORMATION

Supported by clinical studies designed and tested by dentists and dental hygienists1

LISTERINE® Mouthwash does not
decrease salivary flow8

In alcohol and non-alcohol containing mouthwashes

Listerine mouthwash and saliva flow rate chart

LISTERINE® Mouthwash does not
decrease oral pH8

In alcohol and non-alcohol containing mouthwashes

Listerine mouthwash and oral pH chart

*Vs brushing alone.

With brushing in a lab study.

When used twice daily.

Vs brushing alone. In health adults with normal salivary flow.

References: 1. Milleman KR, Bosma ML, DelSasso A, et al. Safety and efficacy of essential oils and zinc containing mouthrinses. Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21-24, 2023; Bogotá, Colombia. 2. Data on file, Johnson & Johnson Consumer Inc. 3. Min K, Bosma ML, DelSasso A, et al. Efficacious plaque control by mouthrinsing vs flossing: quantitative microbiome analysis. Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21-24, 2023; Bogotá, Colombia. 4. Pan P, Barnett ML, Coelho J, Brogdon C, Finnegan MB. Determination of the in situ bactericidal activity of an essential oil mouthrinse using a vital stain method. J Clin Periodontol. 2000;27(4):256-261. 5. Ilg D, Junker L, McGuire JA, et al. In vivo efficacy of an alcohol-free essential oil containing mouthrinse. J Dent Hyg. 2012;86(1):51. 6. Porter SR, Scully C. Oral malodour (halitosis). BMJ. 2006;333(7569):632-635. 7. Allakar RP, Waite RD, Hickling J, et al. Topographic distribution of bacteria associated with oral malodour on the tongue. Arch Oral Biol. 2008;53(suppl):S8-S12. 8. Bosma ML, DelSasso A, McGuire JA, et al. Two-week safety, salivary pH and flow – alcohol/non-alcohol mouthrinses. Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21-24, 2023; Bogotá, Colombia.